Michela Galli
Michela Galli obtained her Bachelor’s degree in Industrial Chemistry from the University of Milan in 2022, followed by a Master’s degree in Chemical Sciences from the same university in 2024. During her Master’s, she carried out her thesis research under the supervision of Prof. Alessandra Silvani, focusing on the design, synthesis, and biological evaluation of proteolysis-targeting chimeras (PROTACs) targeting the enzyme hDASPO.
She is currently pursuing a PhD in Industrial Chemistry at the University of Milan under the supervision of Prof. Alessandra Silvani, where her research focuses on the application of novel methodologies for the design and synthesis of small molecules targeting biological systems.
Michela is currently a visiting PhD Researcher at the Verwilstlab, where she is contributing to the ongoing antimicrobial research in the lab.
CV
Research Interests
PREPRINT. Exploring the use of Cyrene for the amidation of E3 ligase recruiters: efficient access to PROTAC precursors
Michela Galli, Andrea Citarella, Valerio Fasano, Daniele Passarella, Alessandra Silvani, Beilstein Archives 2026, 202626. Read here
3. PROTAC-mediated degradation of peroxisomal d-aspartate oxidase: A novel strategy to modulate d-aspartate homeostasis for schizophrenia treatment
Michela Galli, Valentina Rabattoni, Miriam Cavinato, Francesca Vasile, Irene Gado, Kainat Ulfat, Haidi Shehi, Alessandra Silvani, Daniele Passarella, Andrea Citarella, Loredano Pollegioni, Marco Nardini, European Journal of Medicinal Chemistry 2026, 309, 118720. Read here
2. Synthesis of Sulfonamides in the Biobased Solvent Cyrene
Michela Galli, Andrea Fulminante, Alessandro Fiori, Valerio Fasano, Alessandra Silvani, Daniele Passarella, Andrea Citarella, ChemistryOpen 2026, 15, e70290. Read here
1. Nirmatrelvir: From discovery to modern and alternative synthetic approaches
Michela Galli,† Francesco Migliano,† Valerio Fasano, Alessandra Silvani, Daniele Passarella, Andrea Citarella, Processes 2024, 12, 1242. Read here