Highlights
2024

65. Theranostic Fluorescent Probes
Amit Sharma,† Peter Verwilst, Mingle Li,† Dandan Ma,† Nem Singh, Jiyoung Yoo, Yujin Kim, Ying Yang, Jing-Hui Zhu, Haiqiao Huang, Xi-Le Hu, Xiao-Peng He, Lintao Zeng, Tony D. James, Xiaojun Peng, Jonathan L. Sessler, and Jong Seung Kim, Chemical Reviews 2024. Read here

2023

64. Exploring the Structure-Activity-Relationship of the ‘B’-ring in Diaryl Ether-Based paFabV Inhibitors
Radu-George Bulai, Sofie Heylen, Maria Cremonini, Eveline Lescrinier, Jef Rozenski, Joleen Masschelein,* Peter Verwilst,* ChemRxiv 2023. Read here

2022

63. Targeting chemokine receptors from the inside-out: discovery and development of small-molecule intracellular antagonists
Margaux Billen, Dominique Schols, Peter Verwilst,* Chemical Communications 2022, 58, 4132−4148. Read here

62. Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes
Jusung An,† Peter Verwilst, Hira Aziz,† Jinwoo Shin,† Sungsu Lim, Ilwha Kim, Yun Kyung Kim, Jong Seung Kim, Bioactive Materials 2022,13, 239–248. Read here

61. A fluorescent nanoprobe based on AIEgen: Vizulaization of silver ions and sensing applications in cancer cells and S. aureus.
Na Hee Kim, Rae Hyung Kang, Peter Verwilst,* Dokyoung Kim,* Dyes and Pigments 2022, 198, 110027. Read here

2021

60. Fluorescent Visualization of Nucleolar G-Quadruplex RNA and Dynamics of Cytoplasm and Intranuclear Viscosity
Le Yu,† Peter Verwilst,† Inseob Shim, Yu-Qiang Zhao, Ying Zhou, Jong Seung Kim, CCS Chemistry 2021, 3, 2725–2739. Read here 

59. Calix[n]triazolium based Turn-On Fluorescent Sensing Ensemble for Selective Adenosine Monophosphate (AMP) Detection
Jihee Cho, Jinwoo Shin, Minjung Kang, Peter Verwilst, Changhyun Lim, Hanbin Yoo, Jeung Gon Kim, Xingcai Zhang, Chang Seop Hong, Jong Seung Kim, Sanghee Kim, Chemical Communications 2021, 57, 12139–12142. Read here

58. A Small Molecule Strategy for Targeting Cancer Stem Cells in Hypoxic Microenvironments and Preventing Tumorigenesis
Ji Hyeon Kim,† Peter Verwilst,† Miae Won, Junhyoung Lee, Jonathan L. Sessler, Jiyou Han, Jong Seung Kim, Journal of the American Chemical Society 2021, 143, 14115–14124. Read here

57. Human Glioblastoma Visualization: Triple Receptor-Targeting Fluorescent Complex of Dye, SIWV Tetra-Peptide, and Serum Albumin Protein
Jong Min An,† Heejo Moon,† Peter Verwilst,† Jinwoo Shin, B. Moon Kim, Chul-Kee Park, Jong Seung Kim, Seung Geun Yeo, Hyo Young Kim, Dokyoung Kim, ACS Sensors 2021, 6, 2270–2280. Read here

56. Multichromatic fluorescence towards aberrant proteinaceous aggregates utilizing benzimidazole-based ICT fluorophores
Jusung An, Paramesh Jangili,* Sungsu Lim, Yun Kyung Kim,* Peter Verwilst,* Jong Seung Kim,*, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2021, 101, 205–215. Read here

2020

55. Visualizing mitochondria and mouse intestine with a fluorescent complex of a naphthalene-based dipolar dye and serum albumin
Jong Min An, Heejo Moon, Yejin Kim, Sangrim Kang, Youngseo Kim, Yuna Jung, Sungnam Park, Peter Verwilst,* B. Moon Kim,* Jae Seung Kang,* Dokyoung Kim,* Journal of Materials Chemistry B 2020, 8, 7642−7651. Read here 

54. Crown ether-appended calix[2]triazolium[2]arene as a macrocyclic receptor for the recognition of the H2PO4- anion
Jihee Cho,† Peter Verwilst, Minjung Kang, Jia-Lin Pan, Amit Sharma, Chang Seop Hong, Jong Seung Kim, Sanghee Kim, Chemical Communications 2020, 56, 1038−1041. Read here 

53. In Vitro Activation of Cytochrome P450 46A1 (CYP46A1) by Efavirenz-Related Compounds
Natalia Mast, Peter Verwilst, Clayton J Wilkey, F Peter Guengerich, Irina A Pikuleva, Journal Of Medicinal Chemistry 2020, 63, 6477−6488. Read here 

52. STORM imaging of mitochondrial dynamics using a vicinal-dithiol-proteins-targeted probe
Bingling Chen, Wanjun Gong, Zhigang Yang, Wenhui Pan, Peter Verwilst, Jinwoo Shin, Wei Yan, Liwei Liu, Junle Qu, Jong Seung Kim, Biomaterials 2020, 243, Art: 119938. Read here 

51. MDM2-Associated Clusterization-Triggered Emission and Apoptosis Induction Effectuated by a Theranostic Spiropolymer
Pai Liu, Weiqiang Fu, Peter Verwilst, Miae Won, Jinwoo Shin, Zhengxu Cai, Bin Tong, Jianbing Shi, Yuping Dong, Jong Seung Kim, Angewandte Chemie-International Edition 2020, 59, 8435−8439. Read here 

50. Mitochondrial Relocation of a Common Synthetic Antibiotic: A Non-genotoxic Approach to Cancer Therapy
Kyoung Sunwoo, Miae Won, Kyung-Phil Ko, Miri Choi, Jonathan F Arambula, Sung-Gil Chi,* Jonathan L Sessler,* Peter Verwilst,* Jong Seung Kim,*, Chem 2020, 6, 1408−1419. Read here 

49. Combining viscosity-restricted intramolecular motion and mitochondrial targeting leads to selective tumor visualization
Le Yu, Jun Feng Zhang, Mingle Li, Dewei Jiang, Ying Zhou,* Peter Verwilst,* Jong Seung Kim,*, Chemical Communications 2020, 56, 66846687. Read here 

2019

48. In Vivo Imaging of Endogenously Produced HClO in Zebrafish and Mice Using a Bright, Photostable Ratiometric Fluorescent Probe
Chong Duan,† Miae Won,† Peter Verwilst, Junchao Xu, Hyeong Seok Kim, Lintao Zeng, Jong Seung Kim, Analytical Chemistry 2019, 268, 195−204. Read here

47. Harnessing Intramolecular Rotation To Enhance Two-photon Imaging of A beta Plaques through Minimizing Background Fluorescence
Jinwoo Shin,† Peter Verwilst, Hayoung Choi,† Sangrim Kang, Jiyou Han, Na Hee Kim, Jin Gyu Choi, Myung Sook Oh, Ji Sun Hwang, Dokyoung Kim, Inhee Mook-Jung, Jong Seung Kim, Angewandte Chemie-International Edition 2019, 58, 5648−5652. Read here 

46. Coumarin-Based Small-Molecule Fluorescent Chemosensors
Duxia Cao,† Zhiqiang Liu,† Peter Verwilst, Seyoung Koo, Paramesh Jangili, Jong Seung Kim, Weiying Lin, Chemical Reviews 2019, 119, 10403−10519. Read here 

45. A colorimetric and fluorescent lighting-up sensor based on ICT coupled with PET for rapid, specific and sensitive detection of nitrite in food
Juanjuan Wu,† Lirong Jiang,† Peter Verwilst, Jusung An, Hongyan Zeng, Lintao Zeng, Guangle Niu, Jong Seung Kim, Chemical Communications 2019, 55, 9947−9950. Read here 

44. Enhanced sensitivity of fluorescence-based Fe(II) detection by freezing
Yun Hak Lee, Peter Verwilst, Hyeong Seok Kim, Jinjung Ju, Jong Seung Kim, Kitae Kim, Chemical Communications 2019, 55, 12136−12139. Read here 

43. Revealing Protein Aggregates under Thapsigargin-Induced ER Stress Using an ER-Targeted Thioflavin
Peter Verwilst, Kyutae Kim,† Kyoung Sunwoo, Hye-Ri Kim, Chulhun Kang, Jong Seung Kim, ACS Sensors 2019, 4, 2858−2863. Read here 

42. Ultrasensitive electrochemical genosensor for direct detection of specific RNA sequences derived from avian influenza viruses present in biological samples
Kamila Malecka, Edyta Swieton, Peter Verwilst, Anna Stachyra, Agnieszka Sirko, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Acta Biochimica Polonica 2019, 66, 229−304. Read here 

41. Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble
Ling-Xi Huang, Qing Guo, Yong Chen, Peter Verwilst, Subin Son, Jia-Bin Wu, Qian-Yong Cao, Jong Seung Kim, Chemical Communications 2019, 55, 1413514138. Read here 

2018

40. A two-photon fluorescent probe records the intracellular pH through 'OR' logic operation via internal calibration
Arup Podder, Miae Won, Soobin Kim, Peter Verwilst, Mrinmoy Maiti, Zhigang Yang, Junle Qu, Sankarprasad Bhuniya, Jong Seung Kim, Sensors and Actuators B: Chemical 2018, 268, 195−204. Read here 

39. Organic molecule-based photothermal agents: an expanding photothermal therapy universe
Hyo Sung Jung,† Peter Verwilst, Amit Sharma, Jinwoo Shin, Jonathan L Sessler, Jong Seung Kim, Chemical Society Reviews 2018, 47, 2280−2297. Read here 

38. Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores
Peter Verwilst, Hyeong Seok Kim, Soobin Kim, Chulhun Kang, Jong Seung Kim, Chemical Society Reviews 2018, 47, 2249−2265. Read here 

37. Modulating the GSH/Trx selectivity of a fluorogenic disulfide-based thiol sensor to reveal diminished GSH levels under ER stress
Youngjin Wi, Hoa Thi Le, Peter Verwilst, Kyoung Sunwoo, Seo Jin Kim, Jung Eun Song, Hey Young Yoon, Geon Han, Jong Seung Kim, Chulhun Kang, Tae Woo Kim, Chemical Communications 2018, 54, 8897−8900. Read here 

36. A Fluorescent Cy7-Mercaptopyridine for the Selective Detection of Glutathione over Homocysteine and Cysteine
Shin A Yoon, Wantae Kim, Amit Sharma, Peter Verwilst, Miae Won, Min Hee Lee, Sensors 2018, 18, Art: 2897. Read here 

2017

35. Reconsidering azobenzene as a component of small-molecule hypoxia-mediated cancer drugs: A theranostic case study
Peter Verwilst, Jiyou Han,† Jiyeong Lee, Sora Mun, Hee-Gyoo Kang, Jong Seung Kim, Biomaterials 2017, 115, 104−114. Read here 

34. Targeted combinational therapy inducing mitochondrial dysfunction
Weon Sup Shin,† Soon Ki Park,† Peter Verwilst, Seyoung Koo, Joung Hae Lee, Sung-Gil Chi, Jong Seung Kim, Chemical Communications 2017, 53, 1281−1284. Read here 

33. Photosensitizer localization in amphiphilic block copolymers controls photodynamic therapy efficacy
Vusala Ibrahimova, Sergey A Denisov, Kevin Vanvarenberg, Peter Verwilst, Veronique Preat, Jean-Michel Guigner, Nathan D McClenaghan, Sebastien Lecommandoux, Charles-Andre Fustin, Nanoscale 2017, 9, 11180−11186. Read here 

32. A Mitochondria-Targeted Cryptocyanine-Based Photothermogenic Photosensitizer
Hyo Sung Jung, Jae-Hong Lee, Kyutae Kim, Seyoung Koo, Peter Verwilst, Jonathan L Sessler, Chulhun Kang, Jong Seung Kim, Journal Of The American Chemical Society 2017, 139, 9972−9978. Read here 

31. Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe
Peter Verwilst, Hye-Ri Kim,† Jinho Seo, Nak-Won Sohn, Seung-Yun Cha, Yeongmin Kim, Sungho Maeng, Jung-Won Shin, Jong Hwan Kwak, Chulhun Kang, Jong Seung Kim, Journal Of The American Chemical Society 2017, 139, 13393−13403. Read here 

30. PLK1-Targeted Fluorescent Tumor Imaging with High Signal-to-Background Ratio
Ji-Ting Hou, Kyung-Phil Ko, Hu Shi, Wen Xiu Ren, Peter Verwilst, Seyoung Koo, Jin Yong Lee, Sung-Gil Chi, Jong Seung Kim, ACS Sensors 2017, 2, 1512−1516. Read here 

29. "Electrochemical Biosensor for the Detection of Glycated Albumin
Edyta Mikula, Aleksandra Wyslouch-Cieszynska, Liliya Zhukova, Peter Verwilst, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Current Alzheimer Research 2017, 14, 345−351. Read here 

2016

28. BODIPY/Nile-Red-Based Efficient FRET Pair: Selective Assay of Endoplasmic Reticulum Membrane Fluidity
Zhigang Yang, Youngjin Wi, Young-Min Yoon, Peter Verwilst, Joo Hee Jang, Tae Woo Kim, Chulhun Kang, Jong Seung Kim, Chemistry-An Asian Journal 2016, 11, 527−531. Read here 

27. Fluorescent and colorimetric sensors for the detection of humidity or water content
Hyo Sung Jung,† Peter Verwilst,Won Young Kim, Jong Seung Kim, Chemical Society Reviews 2016, 45, 1242−1256. Read here 

26. Cancer Targeted Enzymatic Theranostic Prodrug: Precise Diagnosis and Chemotherapy
Weon Sup Shin,† Jiyou Han,† Peter Verwilst, Rajesh Kumar, Jong-Hoon Kim, Jong Seung Kim, Bioconjugate Chemistry 2016, 27, 1419−1426. Read here 

25. Coumarin-decorated Schiff base hydrolysis as an efficient driving force for the fluorescence detection of water in organic solvents
Won Young Kim, Hu Shi, Hyo Sung Jung, Daeheum Cho, Peter Verwilst, Jin Yong Lee, Jong Seung Kim, Chemical Communications 2016, 52, 8675−8678. Read here 

24. Mitochondria-targeted aggregation induced emission theranostics: crucial importance of in situ activation
Weon Sup Shin,† Min-Goo Lee,† Peter Verwilst, Joung Hae Lee, Sung-Gil Chi, Jong Seung Kim, Chemical Science 2016, 7, 6050−6059. Read here 

23. A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues
Yun Hak Lee,† Yonghe Tang,† Peter Verwilst, Weiying Lin, Jong Seung Kim, Chemical Communications 2016, 52, 11247−11250. Read here 

2015

22. The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof
Peter Verwilst, Kyoung Sunwoo, Jong Seung Kim, Chemical Communications 2015, 51, 5556−5571. Read here 

21. Recent advances in Gd-chelate based bimodal optical/MRI contrast agents
Peter Verwilst, Soyeon Park, Byungkwon Yoon, Jong Seung Kim, Chemical Society Reviews 2015, 44, 1791−1806. Read here 

20. Highly Selective In Vivo Imaging of Endogenous/Exogenous Phosphate Ion over ATP and PPi
Jun Feng Zhang, Lin E Guo, Tie Nan Zang, Yu Lian Duan, Xin Yi Liu, Zhigang Yang, Peter Verwilst, Kaijun Luo, Guang Ke Wang, Jun Feng Kou, Ying Zhou, Jong Seung Kim, Chemistry-An Asian Journal 2015, 10, 1165−1169. Read here 

19. Organelle-selective di-(2-picolyl)amine-appended water-soluble fluorescent sensors for Cu(II): synthesis, photophysical and in vitro studies
Yun Hak Lee, Peter Verwilst, Nayoung Park, Joung Hae Lee, Jong Seung Kim, Journal Of Inclusion Phenomena And Macrocyclic Chemistry 2015, 82, 109−116. Read here 

18. BODIPY-Coumarin Conjugate as an Endoplasmic Reticulum Membrane Fluidity Sensor and Its Application to ER Stress Models
Hoyeon Lee, Zhigang Yang, Youngjin Wi, Tae Woo Kim, Peter Verwilst, Yun Hak Lee, Ga-in Han, Chulhun Kang, Jong Seung Kim, Bioconjugate Chemistry 2015, 26, 2474−2480. Read here 

17. Anion binding and transport properties of cyclic 2,6-bis(1,2,3-triazol-1-yl)pyridines
Tamara Merckx, Cally JE Haynes, Louise E Karagiannidis, Harriet J Clarke, Katie Holder, Alexandra Kelly, Graham J Tizzard, Simon J Coles, Peter Verwilst, Philip A Gale, Wim Dehaen, Organic & Biomolecular Chemistry 2015, 13, 1654−1661. Read here 

2014

16. Direct Observation of Reversible Electronic Energy Transfer Involving an Iridium Center
Sergey A Denisov, Yanouk Cudre, Peter Verwilst, Gediminas Jonusauskas, Marta Marin-Suarez, Jorge Fernando Fernandez-Sanchez, Etienne Baranoff, Nathan D McClenaghan, Inorganic Chemistry 2014, 53, 2677−2682. Read here 

15. Pentetic acid (DPTA) Cu(II) monolayer deposited on gold electrode-The base of biosensors for electrochemical screening of kinase JAK2 and potential inhibitor interactions
Justyn Wojtasik, Marcin Mielecki, Katarzyna Kurzatkowska, Krystyna Grzelak, Peter Verwilst, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Sensors and Actuators B - Chemical 2014, 196, 223−230. Read here 

14. Voltammetric Detection of S100B Protein Using His-Tagged Receptor Domains for Advanced Glycation End Products (RAGE) Immobilized onto a Gold Electrode Surface
Edyta Mikula, Aleksandra Wyslouch-Cieszynska, Liliya Zhukova, Monika Puchalska, Peter Verwilst, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Sensors 2014, 14, 10650−10663. Read here 

13. Immobilization of His-tagged kinase JAK2 onto the surface of a plasmon resonance gold disc modified with different copper (II) complexes
Katarzyna Kurztkowska, Marcin Mielecki, Krystyna Grzelak, Peter Verwilst, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Talanta 2014, 130, 336−341. Read here 

2013

12. Ruthenium(II) complexes based on tridentate polypyridine ligands that feature long-lived room-temperature luminescence
Giulio Ragazzon, Peter Verwilst, Sergey A Denisov, Alberto Credi, Gediminas Jonusauskas, Nathan D McClenaghan, Chemical Communications 2013, 49, 9110−9112. Read here 

11. Preorganisation in bistriazolyl anion receptors
Tamara Merckx, Peter Verwilst, Wim Dehaen, Tetrahedron Letters 2013, 54, 4237−4240. Read here 

10. Oriented Immobilization of His-Tagged Protein on a Redox Active Thiol Derivative of DPTA-Cu(II) Layer Deposited on a Gold Electrode-The Base of Electrochemical Biosensors
Edyta Mikula, Magdalena Sulima, Ilona Marszalek, Aleksandra Wyslouch-Cieszynska, Peter Verwilst, Wim Dehaen, Jerzy Radecki, Hanna Radecka, Sensors 2013, 13, 11586−11602. Read here 

9. Controlling the self-assembly of cationic bolaamphiphiles: counterion-directed transitions from 0D/1D to exclusively 2D planar structures
Guanglu Wu, Peter Verwilst, Kai Liu, Mario Smet, Charl FJ Faul, Xi Zhang, Chemical Science 2013, 4, 4486−4493. Read here 

8. Synthesis and in vitro evaluation of a PDT active BODIPY-NLS conjugate
Peter Verwilst, Charlotte David, Volker Leen, Johan Hofkens, Peter de Witte, Wim De Borggraeve, Bioorganic & Medicinal Chemistry Letters 2013, 23, 3204−3207. Read here 

2012

7. Bolaamphiphiles Bearing Bipyridine as Mesogenic Core: Rational Exploitation of Molecular Architectures for Controlled Self-Assembly
Guanglu Wu, Peter Verwilst, Jun Xu, Huaping Xu, Ruji Wang, Mario Smet, Wim Dehaen, Charl FJ Faul, Zhiqiang Wang, Xi Zhang, Langmuir 2012, 28, 5023−5030. Read here 

6. A Tripodal Ruthenium-Gadolinium Metallostar as a Potential α(v)β(3) Integrin Specific Bimodal Imaging Contrast Agent
Peter Verwilst, Svetlana V Eliseeva, Luce Vander Elst, Carmen Burtea, Sophie Laurent, Stéphane Petoud, Robert N Muller, Tatjana Parac-Vogt, Wim M De Borggraeve, Inorganic Chemistry 2012, 51, 6405−6411. Read here 

5. Tetranuclear d-f Metallostars: Synthesis, Relaxometric, and Luminescent Properties
Geert Dehaen, Svetlana V Eliseeva, Peter Verwilst, Sophie Laurent, Luce Vander Elst, Robert N Muller, Wim De Borggraeve, Koen Binnemans, Tatjana Parac-Vogt, Inorganic Chemistry 2012, 51, 8775−8783. Read here 

4. Photolariats: synthesis, metal ion complexation and photochromism
Aurelien Ducrot, Peter Verwilst, Luca Scarpantonio, Sebastien Goudet, Brice Kauffmann, Sergey Denisov, Gediminas Jonusauskas, Nathan D McClenaghan, Supramolecular Chemistry 2012, 24, 462−472. Read here 

2011

3. A heterobimetallic ruthenium-gadolinium complex as a potential agent for bimodal imaging
Geert Dehaen, Peter Verwilst, Svetlana V Eliseeva, Sophie Laurent, Luce Vander Elst, Robert N Muller, Wim De Borggraeve, Koen Binnemans, Tatjana Parac-Vogt, Inorganic Chemistry 2011, 50, 10005−10014. Read here 

2. A modular approach towards the synthesis of target-specific MRI contrast agents
Peter Verwilst, Svetlana Eliseeva, Sophie Carron, Luce Vander Elst, Carmen Burtea, Geert Dehaen, Sophie Laurent, Koen Binnemans, Robert Muller, Tatjana Parac-Vogt, Wim De Borggraeve, European Journal of Inorganic Chemistry 2011, 24, 3577−3585. Read here 

2009

1. Synthesis and modifications of a small library of 1,4-benzodiazepin-3-ones toward potential inhibitors of the collagen-von Willebrand Factor interaction
Tiny Deschrijver, Peter Verwilst, Katleen Broos, Hans Deckmyn, Wim Dehaen, Wim De Borggraeve, Tetrahedron 2009, 65, 4521−4529. Read here